Fat collects in lungs of overweight people, raising asthma risk
/Excess weight is hard on the heart, but new research shows it may also harm your lungs.
The study found that higher amounts of fat collect in the airways of overweight and obese people, which may help explain why they're more likely to have wheezing and asthma.
In the study, the investigators analyzed lung samples donated by 52 people for research after their death. Of those, 16 died of asthma, 21 had asthma but died of other causes, and 15 had no asthma.
The findings showed, for the first time, that fatty tissue accumulates in the walls of airways and that the amount of fat in airways increases with body mass index (an estimate of body fat based on weight and height).
The researchers also found that higher levels of fat change the normal structure of airways, resulting in lung inflammation, according to the report published Oct. 17 in the European Respiratory Journal.
"Being overweight or obese has already been linked to having asthma or having worse asthma symptoms. Researchers have suggested that the link might be explained by the direct pressure of excess weight on the lungs or by a general increase in inflammation created by excess weight," explained study co-author Peter Noble. He's an associate professor at the University of Western Australia in Perth.
"This study suggests that another mechanism is also at play. We've found that excess fat accumulates in the airway walls where it takes up space and seems to increase inflammation within the lungs," Noble said in a journal news release.